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Carrier Species

The deer mouse: North America's primary hantavirus carrier

About 10 to 30% of deer mice in endemic areas carry Sin Nombre virus. They shed the virus in urine, droppings, and saliva for weeks to months. Understanding this animal is the first step to prevention.

How to identify a deer mouse

Size: Small, 3 to 4 inches body length (not including tail)
Color: Brown to grayish-brown on top, white belly and feet
Tail: Bicolored: dark on top, white underneath. About the same length as the body.
Ears: Large, prominent ears relative to head size
Eyes: Large, dark, prominent eyes
Droppings: Small, dark, pointed at the ends (about 3-6mm long)

Deer mice look similar to common house mice but are distinguished by their bicolored tail (dark on top, white underneath) and white belly. House mice (Mus musculus) have uniformly colored tails and are generally gray throughout. House mice are not known to carry hantavirus.

Where deer mice live

  • Rural areas: Forests, grasslands, agricultural land, and brushy areas across the western and central US and Canada.
  • Seasonal invaders: They enter homes, cabins, sheds, garages, and barns in fall and winter seeking warmth and food. This is when most human exposures occur.
  • High-risk structures: Rarely used cabins, storage sheds, barns, and outbuildings that sit closed for weeks or months are prime habitats. Opening these buildings without ventilation is a common exposure scenario.
  • Elevation: HPS cases are most common at elevations between 5,000 and 8,000 feet in the Four Corners region (New Mexico, Colorado, Utah, Arizona).

All hantavirus carrier rodents in North America

Deer mouse (Peromyscus maniculatus)

Primary carrier

Virus: Sin Nombre virus | Region: Western and central US, Canada

The primary carrier of hantavirus in North America. Responsible for the vast majority of HPS cases in the US. Found in rural areas, forests, grasslands, and agricultural buildings. Frequently enters homes, cabins, and outbuildings in fall and winter.

White-footed mouse (Peromyscus leucopus)

Virus: New York virus | Region: Eastern US

Carries the New York hantavirus, which causes a milder form of HPS. Common in forests and suburban areas throughout the eastern United States. Often confused with the deer mouse.

Cotton rat (Sigmodon hispidus)

Virus: Black Creek Canal virus | Region: Southeastern US

Found in overgrown fields, ditches, and areas with dense ground cover. Carries a hantavirus strain that rarely causes human disease.

Rice rat (Oryzomys palustris)

Virus: Bayou virus | Region: Southeastern US

A semi-aquatic rodent found in marshy areas of the Gulf Coast region. Carries the Bayou hantavirus, associated with a small number of HPS cases.

How to protect your home

  • • Seal all holes larger than 6mm (1/4 inch) with steel wool, caulk, or metal flashing
  • • Store food in thick plastic or glass containers with tight lids
  • • Keep grass short within 30 feet (10 meters) of your home
  • • Move woodpiles, brush, and junk away from the building
  • • Set snap traps (not live traps) in and around the home if activity is detected
  • • Do not use poison bait inside the home, as mice may die in walls and attract other pests
  • • Ventilate any closed building for 30 minutes before entering